Premium
Intralesional steroids in Langerhans cell histiocytosis of bone
Author(s) -
Bernstrand C,
Björk O,
$Arhström L,
Henter JI
Publication year - 1996
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1996.tb14071.x
Subject(s) - medicine , langerhans cell histiocytosis , histiocytosis , histiocytosis x , surgery , dermatology , pathology , disease
Langerhans cell histiocytosis may involve single or multiple organ systems. Bone involvement is the most common feature. We have examined retrospectively the effects of 20 intralesional injections of steroids into bone in seven patients seen at our department from 1988 to 1993. Most of these injections (75%) relieved the symptoms, and no side‐effects were observed. However, injections into the jaw were seldom effective. Our results suggest that the dose of the steroids administered is of importance.