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Fatal outcome of disseminated Mycobacterium avium infection in childhood. A case of primary incompetent monocyte/macrophage function?
Author(s) -
Heurlin N,
Dahlqvist G,
Elinder G,
Hammarstrom L,
Petrini B
Publication year - 1996
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1996.tb13965.x
Subject(s) - medicine , mycobacterium avium complex , macrophage , primary immunodeficiency , immunology , monocyte , mycobacterium , disease , immunodeficiency , pathology , tuberculosis , immune system , biology , biochemistry , in vitro
Disseminated BCG infection rarely heals, and disseminated disease caused by the Mycobacterium avium complex usually has a poor prognosis with a short time to death. The case of a boy who died after 9 years of diagnosed disseminated M. avium complex infection is described. He showed no signs of previously known immunodeficiency except an incompetent primary monocyte/macrophage function. This case has been commented on in Acta Paediatrica Scandinavia (1982) as “the first infant to survive a generalized BCG infection”