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Risk of asthma in children with a history of croup
Author(s) -
Nicolai T,
Mutius E v
Publication year - 1996
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1996.tb13914.x
Subject(s) - croup , medicine , asthma , family history , odds ratio , pediatrics , provocation test , confidence interval , logistic regression , confounding , pathology , alternative medicine
All fourth‐grade school children in Munich and the surrounding districts (age 9 11 years, n = 9403) were surveyed with a questionnaire, lung function testing and bronchial provocation. Croup was reported in 9.8%. In these children, lung function was decreased even after controlling for asthma and other confounding factors. Only recurrent croup had an increased prevalence in children with asthma. When a family history for asthma, maternal smoking and social status were included into a logistic multiple regression model, the odds ratio to develop asthma was 2.91 (confidence interval (CI) 2.19 3.86) for children with a history of croup, 2.60 (CI 1.93‐3.51) for a family history for asthma and 8.60 (CI 4.99‐14.80) for the combination of family history and croup. Asthma was diagnosed in 37.3% of children with croup and a positive family history.