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Role of amylase‐treated, energy‐dense liquid diet in the nutritional management of acute shigellosis in children: a controlled clinical trial
Author(s) -
Rahman MM,
Mazumder RN,
AH M,
Mahalanabis D
Publication year - 1995
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1995.tb13782.x
Subject(s) - medicine , shigellosis , calorie , randomized controlled trial , shigella , malnutrition , zoology , salmonella , biology , genetics , bacteria
To evaluate if an energy‐dense porridge liquefied by amylase‐rich flour (ARF) from germinated wheat increased the calorie intake in children with acute shigellosis, we studied 66 children, aged 6‐35 months, in a randomized, controlled clinical trial. Children were randomized to receive either an energy‐dense porridge liquefied with ARF (group 1), a thick unaltered porridge (group 2) or a porridge diluted with water (group 3) to a similar viscosity as that in group 1. MeanSD calorie intakes (kJ/kg/ day) from the porridges were 280 113, 167100 and 15180 in groups 1, 2 and 3, respectively (p = 0.006, ANOVA). Total energy intakes (meanSD) from the study diet and other food sources were 469151, 377121 and 351look J/kg/day, respectively (p = 0.006, ANOVA). Intake of breast milk was similar in all groups. Using multiple regression analysis the effect of ARF‐treated energy‐dense porridge in increasing the calorie intake persisted after adjusting for a number of confounders, such as age of the child, isolation of Shigella dysenteriae type 1 and fever. The results of this study suggest that ARF‐treated porridge increases energy intake in infants and young children during acute shigellosis. This feeding approach may be useful in preventing malnutrition following dysentery due to shigellosis. Amylase, energy‐dense, energy intake, liquefied, shigellosisD Mahalanabis, Clinical Sciences Division, International Centre for Diarrhoeal Disease Research, GPO Box 128, Dhaka 1000, Bangladesh