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Coincidental cases of primary sclerosing cholangitis and biliary atresia in siblings?
Author(s) -
Isoyama K,
Yamada K,
Ishikawa K,
Sanada Y
Publication year - 1995
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1995.tb13589.x
Subject(s) - medicine , primary sclerosing cholangitis , biliary atresia , bile duct , gastroenterology , atresia , human leukocyte antigen , pathology , disease , antigen , immunology , liver transplantation , transplantation
Familial cases of primary sclerosing cholangitis or biliary atresia have been reported, although genetic influences and immunopathological abnormalities in these diseases are considered to be obscure. We report a case of primary sclerosing cholangitis and biliary atresia in siblings with the observation of HLA‐DR antigen expression in the abnormal bile duct epithelial cells.