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Age‐related decrease in plasma levels of gastrin, cholecystokinin and somatostatin
Author(s) -
Alfvén G,
Gustavsson P,
UvnäsMoberg K
Publication year - 1995
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1995.tb13566.x
Subject(s) - gastrin , cholecystokinin , somatostatin , medicine , endocrinology , gastrointestinal hormone , hormone , peptide hormone , plasma levels , age groups , secretion , demography , receptor , sociology
Newborn babies have higher concentrations of gastrointestinal hormones than adults. The aim of the present study was to investigate the relationship between age and plasma levels of the three peptides gastrin, cholecystokinin and somatostatin in healthy children aged 1–15 years. Gastrin, cholecystokinin and somatostatin concentrations were twice as high at 1–2 years of age compared with children older than 10 years. Significant negative correlations between age and hormone concentrations were established. It is suggested that these age‐dependent differences are related to the growth rate and relative energy consumption during the early years of life.