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Immunoreactive Copper‐Zinc Superoxide‐dismutase (SOD‐1) in Mosaic Trisomy 21 and Normal Subjects
Author(s) -
BAETEMAN M. A.,
MATTEI M. G.,
BARET A.,
MATTEI J. F.
Publication year - 1984
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1994.tb17745.x
Subject(s) - superoxide dismutase , trisomy , radioimmunoassay , copper , zinc , medicine , chromosome 21 , copper metabolism , microbiology and biotechnology , endocrinology , chromosome , biochemistry , biology , genetics , chemistry , oxidative stress , organic chemistry , gene
. Copper‐zinc superoxide‐dismutase (SOD‐1) (E.C. 1.15.11) levels were measured in 9 children with mosaic trisomy 21 as identified by R, H, G‐banding technics. Radioimmunoassay of erythrocytes and fibroblasts did not demonstrate any significant correlation between levels of SOD‐1 and percentage of trisomic 21 cells in the two target cell populations studied.