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Intestinal Absorption of Vitamin E in Low Birth Weight Infants
Author(s) -
JANSSON L.,
LINDROTH M.,
TYÖPPÖNEN J.
Publication year - 1984
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1994.tb17743.x
Subject(s) - medicine , absorption (acoustics) , birth weight , low birth weight , pediatrics , vitamin , obstetrics , pregnancy , endocrinology , optics , physics , biology , genetics
. Intestinal absorption of dl‐α‐a‐tocopheryl acetate was studied in low birth weight infants. Vitamin E was given from the first day of life, either as a water‐soluble (Ephynal®) or as a lipid‐soluble preparation (E‐vitamin®). Serum‐α‐tocopherol concentrations were determined before treatment and on days three and seven. Treatment with both vitamin E preparations increased serum‐a‐tocopherol on day three and seven. The mean serum‐a‐tocopherol ± SD on day seven were 41.4±10.7 umol/l for the Ephynal® group and 26.7±12.5 umol/l for the E‐vitamin® group, this difference being statistically significant ( p < 0.025). Oral feeding seems to influence the absorption of tocopherol from E‐vitamin®, as the infants with the highest serum‐a‐tocopherol concentrations were those with the highest oral/total feeding ratios. In infants with birth weight <1000 g treatment with 25 mg Ephynal®/day was found to increase serum‐a‐tocopherol on day seven to 46.9± 12.3 umol/l (mean ± SD). This concentration is comparable to those reported by others using higher doses of oral vitamin E.