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Intractable diarrhoea in infancy: a continuing challenge for the paediatric gastroenterologist
Author(s) -
WalkerSmith John A
Publication year - 1994
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1994.tb13220.x
Subject(s) - medicine , enteropathy , villous atrophy , malnutrition , enterocolitis , protein losing enteropathy , pediatrics , biopsy , malabsorption , chronic diarrhea , colonoscopy , gastroenterology , diarrhea , intensive care medicine , disease , coeliac disease , colorectal cancer , cancer
Intractable diarrhoea of infancy is a syndrome of severe chronic diarrhoea, associated with malnutrition, which is not easily resolved by conventional management. Application of small bowel biopsy and colonoscopy with biopsy to children with this syndrome has identified specific entities, such as autoimmune enteropathy and microvillus atrophy. There remains a group of children with unexplained small intestinal enteropathy and idiopathic enterocolitis who pose a considerable problem for diagnosis and management.