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A sibship with recurrent Kawasaki disease and coronary artery lesion
Author(s) -
Matsubara T,
Furukawa S,
Ino T,
Tsuji A,
Park I,
Yabuta K
Publication year - 1994
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1994.tb13194.x
Subject(s) - kawasaki disease , medicine , etiology , disease , coronary artery aneurysm , lesion , pediatrics , coronary artery disease , artery , vascular disease , cardiology , surgery
Although epidemiologic studies of Kawasaki disease suggest an infectious etiology, the cause of this mysterious disease remains unclear. We describe the occurrence of five episodes of Kawasaki disease over a six‐year period in three siblings. Two of the three children experienced recurrent Kawasaki disease and developed coronary artery lesions, which included giant coronary artery aneurysms in the youngest child. The non‐contemporaneous occurrence of the disease in these three children emphasizes the importance of a genetic basis and/or environmental factors in the etiology of Kawasaki disease.