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Neonatal Ureaplasma urealyticum colonization and chronic lung disease
Author(s) -
Jonsson B,
Karell AC,
Ringertz S,
Rylander M,
Faxelius G
Publication year - 1994
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1994.tb13174.x
Subject(s) - ureaplasma urealyticum , medicine , colonization , gestation , gestational age , neonatal intensive care unit , ureaplasma , lung disease , respiratory disease , birth weight , lung , physiology , obstetrics , mycoplasma , pediatrics , pregnancy , microbiology and biotechnology , biology , genetics
We studied Ureaplasma urealyticum colonization in 93 intubated infants (gestational ages 23–40 weeks) in our neonatal intensive care unit by obtaining cultures from endotracheal aspirate and nasopharynx during their first week of life. Eighteen infants had positive cultures, giving a colonization rate of 19%. No infant more than 30 weeks' gestation had a positive culture. The infants with positive cultures had a significantly lower gestational age and birth weight ( p < 0.009 andp < 0.005), with a colonization rate of 33% in infants less than 1000 g. Among the infants with positive cultures, 10 of 17 developed chronic lung disease in contrast with 21 of 72 infants with negative cultures. The development of chronic lung disease and duration of oxygen requirement was strongly associated with immaturity but only weakly with Ureaplasma urealyticum.