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Lipid and apolipoprotein levels and enteral nutrition in very low‐birth‐weight preterm infants
Author(s) -
Decsi T.,
Fekete M.,
Szåsz M.,
Burus I.
Publication year - 1993
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1993.tb18036.x
Subject(s) - medicine , enteral administration , apolipoprotein b , low birth weight , parenteral nutrition , birth weight , pediatrics , cholesterol , pregnancy , biology , genetics
Lipid, lipoprotein cholesterol and apolipoprotein A‐I, A‐II and B levels were determined in 10 very low‐birth‐weight (birth weight 1279 ± 144 g; gestational age 29.2 ± 1.2 weeks, mean ± SD) preterm infants on postnatal days 3, 10 and 21. Feeding with pooled human milk began on day 3 ± 1 and by day 10 all infants were exclusively enterally fed. Both triglyceride and total cholesterol levels increased significantly from day 3 to day 10 (0.84 ± 0.28 versus 1.53 ± 0.72 and 2.42 ± 0.47 versus 3.24 ± 0.80, mmol/l, respectively) ( p <0.01); thereafter no further increase was observed. The increase in total cholesterol level was primarily due to a significant enhancement of very low‐density lipoprotein and low‐density lipoprotein cholesterol (1.52 ± 0.34 versus 2.29 ± 0.73 mmol/l, p< 0.01). Apo A‐I, A‐II and B levels did not change between day 3 and day 10. From day 10 to day 21, however, a significant increase in apo A‐I concentration was noted (0.57 ± 0.20 versus 0.87 ± 0.17 g/l, p< 0.01), whereas apo A‐II levels increased significantly from day 3 to 21 (0.15 ± 0.03 versus 0.27 ± 0.08 g/l, p<0.01). No change in apo B level was seen.