Premium
Severe retinopathy in systemic lupus erythematosus associated with IgG anticardiolipin antibodies
Author(s) -
Ravelli A,
Fuccia G Di,
Caporali R,
Malvezzi F,
Montecucco C,
Martini A
Publication year - 1993
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1993.tb12774.x
Subject(s) - medicine , antibody , lupus erythematosus , anticardiolipin antibodies , immunology , serous fluid , systemic disease , systemic lupus erythematosus , autoantibody , retinopathy , connective tissue disease , immunopathology , autoimmune disease , dermatology , pathology , disease , endocrinology , diabetes mellitus
A six‐year‐old boy with systemic lupus erythematosus developed insidiously a monolateral serous retinal detachment leading to severe visual loss. Serial determinations of anticardiolipin antibodies showed the presence of IgG anticardiolipin antibodies only at the time of ocular involvement. This case underlines the need for regular ophthalmologic evaluation in children with active systemic lupus erythematosus and supports the previous hypothesis of a relationship between antiphospholipid antibodies and retinal involvement in systemic lupus erythematosus.