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School performance and intellectual outcome in adolescents with phenylketonuria
Author(s) -
Weglage J,
Fünders B,
Wilken B,
Schubert D,
Ullrich K
Publication year - 1993
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1993.tb12759.x
Subject(s) - medicine , intelligence quotient , anxiety , pediatrics , population , test (biology) , clinical psychology , psychiatry , paleontology , cognition , environmental health , biology
In a retrospective study, 34 treated adolescents with phenylketonuria and their relatives were tested with scale 2 of the Culture Fair Intelligence Test (CFT 20) and self‐developed questionnaire concerning their development in school. The patients also filled in the Anxiety Questionnaire for Children. With an IQ of 93.6, the patients reached a normal mean intellectual performance but this was significantly below the mean IQ of the general population (100, p < 0.01), the IQ of their mothers (98.2, p < 0.05), their fathers (105.4, p<0.05) and their siblings (110.3, p<0.05 ). The patients' IQs correlated significantly with the IQs of their mothers, the socio‐economic status of their families, the quality of dietary control since birth and the serum phenylalanine concentration at the moment of testing. With respect to age at which the patients started school, type of school attended and number of school years which had to be repeated, there were no significant differences between the patients and their siblings. The patients did not display a markedly higher degree of general anxiety, nervousness at examination time or a greater reluctance to attend school.