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Phosphate, alkaline phosphatase and bone mineralization in preterm neonates
Author(s) -
Ryan SW,
Truscott J,
Simpson M,
James J
Publication year - 1993
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1993.tb12740.x
Subject(s) - alkaline phosphatase , mineralization (soil science) , phosphate , medicine , endocrinology , bone mineral content , bone mineral , inorganic phosphate , phosphatase , elevated alkaline phosphatase , chemistry , enzyme , biochemistry , osteoporosis , organic chemistry , nitrogen
We examined the relationship between bone mineralization, measured by single photon absorptio‐metry, and blood phosphate and alkaline phosphatase concentration in 71 preterm neonates. Although both alkaline phosphatase and phosphate concentrations were significantly related to bone mineral content, and alkaline phosphatase concentrations were related to bone mineral content relative to weight, each could only explain a small amount of the variation in bone mineralization. Hence, concentrations of neither could be used to identify those neonates with the greatest bone mineral deficits.