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Chronic lung disease of preterm infants in Finland is not associated with Ureaplasma Ureaplasma colonization
Author(s) -
Saxén H,
Hakkarainen K,
Pohjavuori M,
Miettinen A
Publication year - 1993
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1993.tb12638.x
Subject(s) - medicine , ureaplasma , colonization , ureaplasma urealyticum , lung disease , mycoplasmataceae , disease , respiratory disease , lung , mycoplasma , mollicutes , microbiology and biotechnology , biology
The occurrence of Ureaplasma Ureaplasma and Mycoplasma hominis in the airways and the association of these microorganisms with chronic lung disease was studied in preterm infants with a gestational age less than 30 weeks. Tracheal aspirates from 49 preterm infants were cultured; 14 (29%) infants were positive for U. Ureaplasma , and 1 (2%) was positive for M. hominis . Of the 16 patients who developed lung disease, 6 (38%) were positive for U. Ureaplasma , while the expected number of Ureaplasma‐ positive patients in this group, based on the overall incidence of Ureaplasma , was 4.6. On the other hand, 8 patients were positive for U. Ureaplasma but did not develop chronic lung disease, nor did samples taken from 10 patients with chronic lung disease show any Ureaplasma growth. From these data we conclude that colonization of the airways with U. Ureaplasma has no significant role in the development of chronic lung disease in preterm infants in the Finnish (Caucasian) population.