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Perinatal factors associated with retinopathy of prematurity
Author(s) -
Gallo JE,
Jacobson L,
Broberger U
Publication year - 1993
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1993.tb12573.x
Subject(s) - retinopathy of prematurity , medicine , gestational age , birth weight , pediatrics , retinopathy , logistic regression , etiology , low birth weight , obstetrics , pregnancy , endocrinology , genetics , biology , diabetes mellitus
The etiology of retinopathy of prematurity appears to be multifactorial. Introduction of new treatments in neonatal care may add new risk factors. We have analyzed thc relationship between 42 perinatal factors and the development of retinopathy of prematurity in 78 infants with a birth weight < 1501 g and/or gestational age < 33 weeks. We have also applied a chronological analysis of the maximum and minimum pO 2 and pCO 2 values. Retinopathy of prematurity was seen in 37 of 78 infants (47.4%). Nineteen factors were found to be related to the development of retinopathy of prematurity. However, when step‐wise logistic regression analysis was used, only birth weight, number of days of oxygen therapy and use of beta‐blocking agents by the mother before birth were found to be associated with the development of retinopathy or prematurity. The results suggest that medication with beta blockers immediately before birth should be used cautiously.