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D‐Lactic acidosis: a treatable encephalopathy in pediatric patients
Author(s) -
Gurevitch J,
Sela B,
Jonas A,
Golan H,
Yahav Y,
Passwell JH
Publication year - 1993
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1993.tb12538.x
Subject(s) - medicine , lactic acidosis , encephalopathy , acidosis , intensive care medicine , pediatrics
A 20‐month old infant, who had short bowel syndrome following extensive surgery for a mid gut volvulus, developed hyperchloremic acidosis, with a large anion gap after enteral feeding was instituted. The organic acidosis was at least partly due to an increased concentration of D‐lactic acid. This patient, as did five other pediatric patients, presented with a typical encephalopathy syndrome. Early recognition of this syndrome and treatment with an intestinal antibiotic and discontinuation of enteral feeding enabled prompt correction of the hyperchloremic acidosis and a rapid clinical recovery.