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Effect of melanin, oxyhemoglobin and bilirubin on transcutaneous bilirubinometry
Author(s) -
Onks D,
Silverman L,
Robertson A
Publication year - 1993
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1993.tb12507.x
Subject(s) - medicine , bilirubin , melanin , serum bilirubin , in vitro , pigment , biochemistry , chemistry , organic chemistry
To determine the effect of skin pigments on transcutaneous bilirubinometer readings, we measured the effect of bilirubin, melanin, and oxyhemoglobin solutions on transcutaneous bilirubinometer readings in vitro. Our results showed that the variability of the readings in vitro was related to the instrument's non‐linear response to bilirubin and melanin concentration and an inacurate oxyhemoglobin correction factor. These factors should be considered in developing a more accurate non‐invasive method of monitoring serum bilirubin concentration.