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Lumbar bone mineral content measured by dual energy X‐ray absorptiometry in newborns and infants
Author(s) -
Salle Bernard L,
Braillon Pierre,
Glorieux Francis H,
Brunet Jacques,
Cavero Eduardo,
Meunier Pierre J
Publication year - 1992
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1992.tb12152.x
Subject(s) - medicine , bone mineral , bone mineral content , dual energy x ray absorptiometry , gestational age , lumbar , birth weight , lumbar spine , lumbar vertebrae , dual energy , nuclear medicine , pediatrics , radiology , surgery , osteoporosis , pregnancy , biology , genetics
Dual energy X‐ray absorptiometry (DXA), a non‐invasive method for measuring small amounts of mineral, was used to assess the bone mineral content (BMC) and bone mineral density (BMD) of the lumbar spine (5 vertebrae) in 57 newborns (on day 1‐2) and 22 infants (1‐24 months of age). A modified high‐resolution program (Hologic) allowed us to assess BMC and BMD with a precision higher than 2.4% and 1.5%, respectively. In newborns, BMC and BMD correlated positively with birth weight, body area, length and gestational age: r = 0.73, 0.71, 0.63 and 0.60, respectively, for BMC; and r =0.59, 0.58, 0.54 and 0.53, respectively, for BMD. In infants, both BMC and BMD were highly correlated with weight, age, length and body area over two years ( r = 0.94 or better in each instance). The data provide normal values for lumbar spine BMC and BMD in newborns (gestational age 31‐40) and infants up to two years of age; DXA appears to be an excellent and safe tool for pediatric bone mineral measurements.