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Recurrent Herpes Simplex Virus Type 2 Encephalitis in a Preterm Neonate: Favourable Outcome after Prolonged Acyclovir Treatment
Author(s) -
BERGSTRÖM T.,
TROLLFORS B.
Publication year - 1991
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1991.tb11966.x
Subject(s) - medicine , encephalitis , herpes simplex virus , aciclovir , serology , pediatrics , herpesviridae , virus , alphaherpesvirinae , virology , viral disease , hsl and hsv , immunology , antibody
. We describe a case of recurrent herpes simplex virus type 2 (HSV‐2) central nervous system infection in a preterm neonate. On two occasions, encephalitis occurred together with eruption of vesicles on the right arm, and the patient was treated with acyclovir. New recurrences of vesicles followed each attempt to discontinue antiviral treatment, and prompted a continuous long‐term acyclovir prophylaxis. At three years of age, the patient has developed normally. The use of immunoblotting for serologic diagnosis of neonatal HSV‐2 infection is demonstrated.