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Breast Feeding Modifies Production of SlgA Cow's Milk‐Antibodies in Infants
Author(s) -
RENZ H.,
BREHLER C.,
PETZOLDT S.,
PRINZ H.,
RIEGER C. H. L.
Publication year - 1991
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1991.tb11825.x
Subject(s) - medicine , saliva , breast milk , casein , breast feeding , beta lactoglobulin , physiology , antibody , milk protein , food science , immunology , pediatrics , biology , whey protein , biochemistry
. One hundred and fifty‐eight healthy mature newborns were divided into 3 groups according to their risk of allergy: Group A, no risk ( n =62), group B, low risk ( n = 30) and Group C, high risk ( n = 66). Saliva was collected at birth and after 3 and 6 months. SIgA anti‐casein and anti‐β‐lactoglobulin were determined by direct ELISA technique. The highest concentrations of secretory antibodies were measured after birth. After 3 months, breast fed infants had lower salivary SIgA anti‐casein concentrations than the group receiving cow's milk ( p ≤0.01). The effect of breast‐feeding was seen even after nursing period of only 3 weeks. Infants without risk of allergy fed cow's milk exclusively had higher SIgA anti‐casein ( p < 0.03) and anti‐β‐lactoglobulin concentrations than low risk infants at the age of 6 months. These data show modifying effect of breast feeding on salivary SIgA production against cow's milk protein.