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Influence of Baseline Lung Function on Exercise‐Induced Response in Childhood Asthma
Author(s) -
LINNA OLAVI
Publication year - 1990
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1990.tb11532.x
Subject(s) - medicine , asthma , lung function , airway obstruction , airway , cardiology , exercise induced asthma , respiratory system , pulmonary function testing , physical exercise , lung , physical therapy , anesthesia
. The dependence of bronchial reactivity to exercise on baseline lung function was studied in 84 asthmatic children aged 7–16 years. The percentage fall in PEF values after a standard exercise running test was 8.4± 8.6 % in the 39 children with an attack rate of less than 10 per year and 29.6±23.3% in the 45 children with an attack rate of 10 or more per year (p<0.001). A significant negative correlation (r=‐0.46, p<0.001) was found for pre‐exercise MMEF and other sensitive tests of airway calibre with the response to exercise, but no such correlation was found between baseline PEF or SG aw values and the exercise response. These results show that bronchial hyperreactivity to exercise is dependent on residual airway obstruction, but a wide variety of reactivity can occur. If the baseline flow‐values are less than three standard deviations below the mean reference, however, a clinically significant response to exercise can be predicted.