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Fibrodysplasia Ossificans Progressiva An 11‐Year‐Old Boy Treated with a Diphosphonate
Author(s) -
BRUNI L.,
GIAMMARIA P.,
TOZZI M. C.,
CAMPARCOLA D.,
SCOPINARO F.,
IMPERATO C.
Publication year - 1990
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1990.tb11371.x
Subject(s) - fibrodysplasia ossificans progressiva , medicine , ossification , heterotopic ossification , myositis ossificans , surgery , thorax (insect anatomy) , dermatology , anatomy
. Fibrodysplasia ossificans progressiva (FOP) is a severe, rare, autosomal dominant, ectopic ossifying condition, with primary involvement of the skeletal muscles associated with skeletal abnormalities. This report concerns an 11‐year‐old boy suffering from FOP, who presented signficant modification of the musculoskeletal structure of the thorax and problems with articular movements. The patient showed progress after treatment with ethane‐l‐hydroxyl, l‐diphosphonate (EHDP). In fact, using a scintiscanner we were able to observe a significant improvement in symptoms and a recovery of some of the active sites of ossification.