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Dexamethasone in the Treatment of Bronchopulmonary Dysplasia
Author(s) -
BENINI FRANCA,
RUBALTELLI F. F.,
GRIFFITH P.,
SALA MARIELLA,
ZORZI C.
Publication year - 1989
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1989.tb11290.x
Subject(s) - dexamethasone , medicine , bronchopulmonary dysplasia , anesthesia , corticosteroid , surgery , gestational age , pregnancy , biology , genetics
Benini, F., Rubaltelli, F. F., Griffith, P., Sala, M. and Zorzi, C. (Department of Paediatrics, University of Padova, Italy). Dexamethasone in the treatment of bronchopulmonary dysplasia. Acta Paediatr Scand Suppl 360: 108, 1989. Sixteen chronically ventilator‐dependent newborns with BPD were treated with one or more cycles of dexamethasone (0.5 mg/kg/day). In 11 cases extubation was possible during the therapy period. Ventilatory parameters were lowered in 3 other newborns. FIO 2 , respiratory rate, PIP, and PEEP, assessed before and after dexamethasone administration, decreased in a statistically significant way. Our data confirm the utility of dexamethasone in the extubation in chronically ventilated infants with BPD.