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Parental Heights of Children with Idiopathic Growth Hormone Deficiency: Analysis from the Kabi International Growth Study
Publication year - 1989
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1989.tb11269.x
Subject(s) - ighd , medicine , growth hormone , hormone , growth hormone deficiency , pediatrics , growth velocity , endocrinology
International Board, Kabi International Growth Study (Kabi, Stockholm, Sweden). Parental heights of children with idiopathic growth hormone deficiency: analysis from the Kabi International Growth Study. Acta Paediatr Scand [Suppl] 356: 178, 1989. In an international study of children treated with growth hormone (GH), parental heights of 554 children with idiopathic growth hormone deficiency (IGHD) and of 248 children with secondary or‘organic’growth hormone deficiency (OGHD) were ascertained. The maternal height SDS of IGHD children was ‐0.41 ± 1.26 (mean ± SD) and the maternal height SDS of OGHD children was 0.03 ± 1.11 ( p < 0.006). Paternal height SDS of IGHD children was ‐0.19 ± 1.08, and paternal height SDS of OGHD children was 0.15 ± 1.08 ( p < 0.006). Adverse deliveries were associated with significantly shorter mothers ( p = 0.04) and a greater discrepancy between paternal and maternal heights ( p < 0.006).