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Pituitary Enlargement, Hypertrichosis and Blunted Growth Hormone Secretion in Primary Hypothyroidism
Author(s) -
NISHI Y.,
HAMAMOTO K.,
KAJIYAMA M.,
FUJITA A.,
KAWAMURA I.,
KAGAWA Y.,
KAJIMA T.,
YAMANAKA M.,
UOZUMI T.
Publication year - 1989
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1989.tb10904.x
Subject(s) - medicine , hypertrichosis , endocrinology , thyroid , hormone , growth hormone , acromegaly , hyperplasia , pituitary gland , hormone therapy , secretion , hormone replacement therapy (female to male) , testosterone (patch) , cancer , breast cancer
ABSTRACT. Pituitary hyperplasia, hypertrichosis and blunted growth hormone (GH) secretion were observed in three children with untreated primary hypothyroidism. These abnormalities disappeared and improved after thyroid hormone therapy. The recognition of these associations may eliminate unnecessary surgery and GH therapy and lead to the choice of thyroid hormone replacement therapy.