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Protein C Activity and Antigen in Premature and Fullterm Newborn Infants
Author(s) -
BENNHAGEN R.,
HOLMBERG L.
Publication year - 1989
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1989.tb10883.x
Subject(s) - medicine , gestational age , gestation , premature newborn , pediatrics , physiology , pregnancy , biology , genetics
. Blood was obtained from 23 premature infants (birthweights 950–2910 g at 26–35 gestational weeks), and 27 fullterm infants (birthweights 2930–4900 g at 37–42 gestational weeks). Protein C concentration and activity were analysed. In preterm infants, protein C concentrations were 2.9–24% of adult values, and those of protein C activity 6–32%, the corresponding figures for term infants being 16–60% and 8.5–60%. Protein C concentrations were below 10% of adult values in four low birthweight infants, three of whom had significant haemorrhages. Protein C activity was below 10% of adult values in three infants, all of whom suffered from major haemorrhages.