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P‐fimbriated Escherichia coli in Children with Acute Cystitis
Author(s) -
LIDEFELT K.J.,
BOLLGREN I.,
KÄLLENIUS G.,
SVENSON S. B.
Publication year - 1987
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1987.tb10564.x
Subject(s) - medicine , escherichia coli , urinary system , virulence , acute cystitis , bacteriology , virulence factor , microbiology and biotechnology , pathogenesis , bacteria , biology , gene , biochemistry , genetics
P‐fimbriation of Escherichia coli is an important factor in the pathogenesis of childhood pyelonephritis. The present study investigates children with single episodes of symptomatic non‐febrile urinary tract infection, i.e. cystitis, with respect to clinical appearance and bacteriology, especially the frequency of P‐fimbriated E. coli. The study included 75 children, 57 of whom had their first attack of urinary tract infection. E. coli was the causative agent in 88% (66/75) of the infections, and 48% (32/66) of E. coli strains were P‐fimbriated. No association was found between identification of P‐fimbriated E. coli at index infection and proneness to reinfection during the following six‐month period. It is suggested that P‐fimbriated E. coli is a virulence factor even in lower urinary tract infections, when occurring in single, symptomatic episodes.