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Evidence for Colonic Absorption of Protein Nitrogen in Infants
Author(s) -
HEINE W.,
WUTZKE K. D.,
RICHTER I.,
WALTHER F.,
PLATH C.
Publication year - 1987
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1987.tb10558.x
Subject(s) - absorption (acoustics) , medicine , nitrogen , gastroenterology , chemistry , physics , organic chemistry , acoustics
The absorption of protein nitrogen by the colon was assessed in 6 infants with colostomy by giving 15 N yeast protein in a dosage of 5–20 mg 15 N/kg (92.4 atom‐% 15 N). The absorption of 15 N ranged between 87.1 and 98.1% of the administered dose, and the retention in the protein pool ranged between 79.0 and 94.2%. The incorporation of 15 N in the plasma proteins was demonstrated by 15 N excess values between 0.02 and 0.10 atom‐%. The results suggest that the colon can assimilate proteins when insufficient absorption of protein nitrogen in the small intestine occurs. The breakdown of protein is thought to result from the action of colonic flora.