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Comparison of Different Rates of Artificial Ventilation in Preterm Neonates with Respiratory Distress Syndrome
Author(s) -
GREENOUGH A.,
POOL J.,
GREENALL F.,
MORLEY C.,
GAMSU H.
Publication year - 1987
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1987.tb10553.x
Subject(s) - medicine , respiratory distress , ventilation (architecture) , artificial ventilation , mechanical ventilation , intensive care medicine , respiratory system , pediatrics , emergency medicine , respiratory disease , anesthesia , lung , mechanical engineering , engineering
The effectiveness of three different ventilator rates of artificial ventilation (30, 60 and 120/min) was studied in 32 preterm infants, all of whom were suffering from the Respiratory Distress Syndrome (16 were paralysed). Ventilator pressures, I: E ratio and MAP were kept constant at each rate. Increase in rate from 30 to 60 and to 120/min was well tolerated and not associated with episodes of hypotension. The only significant improvement in oxygenation was amongst the non‐paralysed infants and at a rate of 120/min ( p <0.01) this was associated with synchronous respiration. Two different ventilators were used in the study and a significant change in Pa co2 , (reduction) occurred only in non‐paralysed infants ventilated at a rate of 120/min by Sechrist ventilators ( p <0.05). This difference may be a direct reflection of differences in ventilator performance at fast rates.