Premium
Urinary C‐Peptide Excretion at Onset of Insulin Dependent Diabetes Mellitus in Children
Author(s) -
IVARSSON S. A.,
JOHANSSON E.,
NILSSON K. O.,
THORELL J. I.
Publication year - 1987
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1987.tb10529.x
Subject(s) - medicine , excretion , c peptide , endocrinology , diabetes mellitus , urinary system , peptide , insulin , urine , chemistry , biochemistry
. The 24‐hour urinary excretion of C‐peptide and the plasma C‐peptide concentration were measured at the onset of insulin dependent diabetes mellitus (IDDM) in children. The excretion of C‐peptide was twice as high as that found in normal control subjects, whereas the plasma C‐peptide values were markedly lower, indicating increased urinary leakage of C‐peptide in this phase of the disease. In the diabetic children under seven years of age the mean value of C‐peptide excretion was clearly lower than in the older children.