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Beneficial Effects of Palatable Guar and Guar Plus Fructose Diets in Diabetic Children
Author(s) -
PAGANUS A.,
MÄENPÄÄ J.,
ÅKERBLOM H. K.,
STENMAN U.H.,
KNIP M.,
SIMELL O.
Publication year - 1987
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1987.tb10418.x
Subject(s) - guar , medicine , diabetes mellitus , guar gum , endocrinology , fructose , insulin , food science , chemistry , pathology
This randomized cross‐over study evaluates the effects of extended, guar and guar + fructose diets on the metabolic balance of children with insulin‐dependent diabetes mellitus (IDDM). We studied 22 children; mean age 12.2 years, mean duration of diabetes 4.4 years. The diet was supplemented for three weeks with guar in palatable form (5% of daily carbohydrate intake) and with guar + fructose (1 g of fructose/kg body weight, max 30 g/d) for another three weeks. A control group (8 children, mean age 12.3, duration of diabetes 4.3 years) followed the same experimental protocol without guar supplementation. The metabolic balance was assessed by glucosuria index (per cent of tests with less than 1% glucosuria from all urine tests) and measurements of red cell glycohaemoglobin A 1c (HbA 1c ). Serum total and HDL‐choiesterol, C‐peptide, pancreatic and enteroglucagon were also measured. HbA 1c decreased during guar ( p <0.001) and guar + fructose diet ( p <0.001). The glucosuria index improved ( p <0.02) and the serum total cholesterol concentration decreased ( p <0.02) during the experimental guar diets. Guar in acceptable form and quantity in the diet appears to improve metabolic control of diabetic children.