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Efficiency of Ventilation in Neonatal Pulmonary Maladaptation
Author(s) -
SANDBERG K.,
SJÖQVIST B. A.,
HJALMARSON O.,
OLSSON T.
Publication year - 1987
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1987.tb10410.x
Subject(s) - nitrogen washout , medicine , maladaptation , functional residual capacity , ventilation (architecture) , dead space , airway , pulmonary function testing , washout , anesthesia , physiology , lung , intensive care medicine , lung volumes , mechanical ventilation , mechanical engineering , psychiatry , engineering
ABSTRACT. Lung physiology was studied in sixteen infants with pulmonary maladaptation (PMA) during the course of the disease and after clinical recovery. A sensitive nitrogen washout method was used. During the disease the infants showed reduced ventilatory efficiency and increased dead space. Total ventilation increased simultaneously, while alveolar ventilation was maintained. The majority of the infants showed greater functional residual capacity during the disease than after clinical recovery. The results suggest that gas mixing efficiency is impaired in infants with PMA and that this might be due to effects on the small airway function in the lungs.