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Hypodipsic Hypernatremia Associated with Absence of Septum Lucidum and Olfactory Dysfunction
Author(s) -
OHZEKI T.,
HANAKI K.,
ASANO T.,
ISHITANI N.,
WAKATSUKI H.,
SHIRAKI K.
Publication year - 1986
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1986.tb10341.x
Subject(s) - hypernatremia , medicine , hyposmia , vasopressin , hyponatremia , abnormality , endocrinology , antidiuretic , anesthesia , sodium , chemistry , organic chemistry , psychiatry , disease , covid-19 , infectious disease (medical specialty)
. A case of hypodipsic Hypernatremia in a 16‐month‐old Japanese boy is reported. Partial antidiuretic hormone deficiency was present. Computed tomography of the brain revealed absence of septum lucidum. No ophthalmological abnormality could be found. He had hyp‐osmia, which has not been reported previously in association with Hypernatremia due to hypodipsia. Forced fluid administration and nasal l‐deamino‐8‐d‐arginine vasopressin treatment could maintain serum electrolyte levels within normal ranges. However, episodes of Hypernatremia could not be completely avoided while he was treated with l‐deamino‐8‐d‐arginine vasopressin and ad libitum oral fluid.