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Dysgenesis of the Corpus Callosum and Hypopituitarism
Author(s) -
SMITH P. J.,
HINDMARSH P.,
KENDALL B.,
BROOK C. G. D.
Publication year - 1986
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1986.tb10318.x
Subject(s) - medicine , hypopituitarism , corpus callosum , dysgenesis , gonadal dysgenesis , anatomy , pediatrics
. A high resolution CT scan demonstrated the unexpected finding of dysgenesis of the corpus callosum in addition to the expected finding of pituitary hypoplasia in three children who presented with growth failure secondary to hypopituitarism. Several of the clinical features reported in association with dysgenesis of the corpus callosum may be ascribed to hypo‐thalamo‐pituitary dysfunction. These children emphasize the need to assess the endocrine function of patients with midline structural defects. It should not be assumed that the clinical manifestations are related solely to the anatomical abnormality.