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15 N Tracer Investigations of the Physiological Availability of Urea Nitrogen in Mother's Milk
Author(s) -
HEINE W.,
TIESS M.,
WUTZKE K. D.
Publication year - 1986
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1986.tb10227.x
Subject(s) - urea , feces , excretion , nitrogen , tracer , nitrogen balance , medicine , labelling , urine , zoology , blood urea nitrogen , endocrinology , chromatography , biochemistry , chemistry , kidney , biology , organic chemistry , microbiology and biotechnology , physics , nuclear physics
. The physiological availability of urea in mother's milk was investigated in tracer studies using [ 15 N] 2 urea and involving 22 infants. The incorporation of 15 N into the body protein was established in 16 subjects by emission spectrophotometrical determination of the 15 N excess in the serum protein. Between 2 % and 3.6 % of the serum protein is synthesized from the urea nitrogen in mother's milk. In further studies on the 15 N balance in 6 infants, renal excretion of 15 N after oral multiple and single impulse labelling with [ 15 N] 2 urea constituted 60 % of the dose administered. Three‐tenths –2.5 % was excreted in the feces. The retention of 15 N in the protein pool varied between 16.7 and 61.4 %