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Oral Rehydration Therapy in Infectious Diarrhoea
Author(s) -
SÖKÜCÜ S.,
MARIN L.,
GUNOZ H.,
APERIA A.,
NEYZI O.,
ZETTERSTROM R.
Publication year - 1985
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1985.tb11015.x
Subject(s) - medicine , rotavirus , sodium , dehydration , gastroenterology , etiology , urine , diarrhea , biochemistry , chemistry , organic chemistry
. The clinical response and changes in water and salt homeostasis as judged from serum sodium levels, salt and water retention and renal handling of sodium was studied during 36 hours following the start of oral rehydration therapy (ORT) with a solution containing 60 mmol N d (ORS,) in 17 well‐nourished, moderately dehydrated Turkish infants aged 3 to 15 months who had acute infectious diarrhoea (7 with rotavirus, 3 with enteropathogenic E. coli 0 111: B 84, and one with enteropathogenic E. coli 0 125: B 15, one with salmonella and 5 of unknown etiology. In the sucessfully treated patients sodium and water balance was normalized within 36 hours. In the cases with hypernatremic dehydration the serum sodium concentration rapidly became normal. The results were compared with those obtained in a previous study of the same type of patients who were rehydrated with a solution containing 90 mmol N d (ORSw). Although retention was considered to be satisfactory after OR& it was less than after ORSw. The changes in the fractionary urinary sodium excretion and the potassium sodium quotient in the urine indicated a less rapid normalization after ORS, than after ORSW.