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Fluctuation of Specific IgA Antibodies in Human Milk
Author(s) -
CRUZ J. R.,
ARÉVALO CAROLINA
Publication year - 1985
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1985.tb10055.x
Subject(s) - secretory iga , antibody , medicine , shigella flexneri , breast milk , immunoglobulin a , breast feeding , specific antibody , shigella , immunology , toxin , microbiology and biotechnology , escherichia coli , physiology , biology , immunoglobulin g , pediatrics , biochemistry , gene
.The concentration of secretory IgA and the levels of IgA specific antibodies against Escherichia coli labile‐toxin, Shigella flexneri 6, and rotaviruses were determined in milk samples obtained serially from women during the first 16 weeks postpartum. The mean concentration of secretory IgA followed the expected pattern; the levels of specific antibodies fluctuated in an unpredictable manner and independently of milk secretory IgA content, becoming undetectable in many instances. Under some circumstances, continued breast‐feeding may not guarantee continued intake of antibodies against intestinal pathogens by the breast‐fed infant.