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Plasma Valine and Urinary C‐Peptide in Breast‐fed and Artificially Fed Infants up to 6 Months of Age
Author(s) -
GINSBURG B. E.,
LINDBLAD B. S.,
LUNDSJÖ A.,
PERSSON B.,
ZETTERSTRÖM R.
Publication year - 1984
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1984.tb09931.x
Subject(s) - valine , creatinine , urine , medicine , c peptide , endocrinology , urinary system , excretion , peptide , amino acid , insulin , chemistry , biochemistry
. Plasma branched‐chain amino acids and urinary C‐peptide‐creatinine excretion was determined at 3, 41/2 and 6 months of age in a group of 50 infants who were either breast‐fed or artificially fed and selected at random. The average concentrations of valine in plasma and C‐peptide in urine as well as the ratio between C‐peptide and creatinine in urine were 2–3 times higher ( p < 0.01) in artificially fed as compared to breast‐fed infants at all the ages studied. Plasma valine values correlated significantly with the urinary C‐peptide/creatinine ratio ( r = 0.76, p < 0.01), which suggests that the enhanced insulin response induced by the artificial formula is related to its protein content.

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