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Pseudomembranous Colitis with Recurring Diarrhoea and Prolonged Persistence of Clostridium Difficile in A 10‐Year‐Old Girl
Author(s) -
VESIKARI T.,
MAKI M.,
BAER MÄIJA,
GRÖNROOS P.
Publication year - 1984
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1984.tb09913.x
Subject(s) - pseudomembranous colitis , clostridium difficile , medicine , colitis , vancomycin , diarrhea , gastroenterology , girl , persistence (discontinuity) , surgery , antibiotics , microbiology and biotechnology , bacteria , staphylococcus aureus , developmental psychology , genetics , geotechnical engineering , engineering , biology , psychology
. A 10‐year‐old girl developed, after treatment with amyxocillin, a clinically and sigmoidoscopi‐cally apparent pseudomembranous colitis with positive Clostridium difficile stool culture. Treatment with vancomycin resulted in rapid clinical cure, but there was a relapse of diarrhoea and reappearance of C. difficile , with no pseudomembranous colitis, within one month. Clinical symptoms subsided spontaneously but C. difficile persisted for 2 more months in the stools. This case reflects three different aspects of C. difficile infection in one child: pseudomembranous colitis, ordinary diarrhoea, and symptomless carrier state.

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