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Deterioration in Lung Function after General Anaesthesia in Patients with Cystic Fibrosis
Author(s) -
RICHARDSON V. F.,
ROBERTSON C. F.,
MOWAT A. P.,
HOWARD E. R.,
PRICE J. F.
Publication year - 1984
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1984.tb09901.x
Subject(s) - medicine , vital capacity , cystic fibrosis , sclerotherapy , portal hypertension , varices , lung function , anesthesia , pulmonary function testing , general anaesthesia , expiration , lung volumes , lung , cardiology , respiratory system , surgery , cirrhosis , diffusing capacity
. 48 hours after oesophagoscopy and injection sclerotherapy of oesophageal varices under general anaesthesia, 11 studies of 6 children ith cystic fibrosis and portal hypertension showed a significant deterioration in 4 tests of lung function. The largest falls were seen in Forced Expiration Volume in one second ( p <0.01) and Forced Expiratory Flow between 25 % and 75 % of Vital Capacity ( p <0.02). In 14 studies of 10 children with portal hypertension from other causes a significant fall occurred only in Peak Expiratory Flow Rate ( p <0.01). The slight falls in Forced Expiratory Volume in one second and Forced Expiratory Flow between 25 % and 75 % of vital capacity were significantly smaller than those observed in the patients with cystic fibrosis ( p <0.05; p <0.01).