Premium
In Search of a Super Solution: Controlled Trial of Glycine‐Glucose Oral Rehydration Solution in Infantile Diarrhoea
Author(s) -
PATRA F. C.,
MAHALANABIS D.,
JALAN K. N.,
SEN A.,
BANERJEE P.
Publication year - 1984
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1984.tb09891.x
Subject(s) - medicine , glycine , infantile diarrhea , pediatrics , diarrhea , intensive care medicine , gastroenterology , biochemistry , amino acid , chemistry
In a double blind trial a glycine fortified oral glucose electrolyte solution was evaluated in a group of infants and small children (n = 25) with moderate to severe dehydration due to acute diarrhoea, and was compared with a matched control group (n = 26) receiving only glucose based oral rehydration solution. It is seen that the diarrhoea stool output, duration of diarrhoea, and volume of oral rehydration fluid required to achieve and maintain hydration are significantly lower in the group receiving glycine fortified glucose electrolyte solution. The possibility of developing an oral rehydration solution which could also act as an absorption promoting drug is discussed.