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CYSTIC FIBROSIS MIMICKING BARTTER'S SYNDROME
Author(s) -
DAVISON A. G.,
SNODGRASS G. J. A. I.
Publication year - 1983
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1983.tb09814.x
Subject(s) - medicine , sweat , cystic fibrosis , hyperaldosteronism , endocrinology , bartter syndrome , sodium , bartter's syndrome , metabolic alkalosis , dehydration , aldosterone , plasma renin activity , alkalosis , hyponatremia , renin–angiotensin system , blood pressure , hypokalemia , biochemistry , biology , chemistry , organic chemistry , acidosis
. A four‐month‐old female presented with dehydration and an unexplained hypoelectrolytaemia and metabolic alkalosis in association with hyperreninaemia and hyperaldosteronism. These findings suggested Bartter's syndrome. Sweat sodium concentrations were within normal limits. Total skin water loss was estimated and found to be sufficient for the sodium loss in the sweat to exceed the dietary intake. Reinvestigation at three years revealed normal plasma electrolytes, plasma renin activity and aldosterone values but sweat sodium concentrations were in excess of 80 mmol/I, indicating a diagnosis of cystic fibrosis.