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PLASMA CONCENTRATIONS OF VITAMIN D METABOLITES IN A CASE OF RICKETS OF PREMATURITY
Author(s) -
MARKESTAD T.,
AKSNES L.,
FINNE P. H.,
AARSKOG D.
Publication year - 1983
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1983.tb09808.x
Subject(s) - rickets , medicine , vitamin d and neurology , calcifediol , endocrinology , calcium , vitamin , vitamin d deficiency , physiology
. Rickets was diagnosed in an extremely low‐birthweight infant 16 weeks after birth. She had a normal plasma concentration of 25‐hydroxyvitamin D, a relatively low level of 24,25‐dthy‐droxyvitamin D, and a markedly elevated 1,25‐dihydroxyvitamin D level compared with adult standards. The plasma concentrations of the vitamin D metabolites were, however, indistin‐guishable from those of healthy preterm infants who received a similar diet of human milk and vitamins. The results indicate that rickets was not caused by vitamin D deficiency or by abnormal vitamin D metabolism, but by calcium and/or phosphate deficiency, and that the calcium and phosphorous content of human milk may be inappropriately low for very low‐birthweight infants.