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TRI‐IODOTHYRONINE AND THYROXINE IN HUMAN MILK
Author(s) -
JANSSON L.,
IVARSSON S.,
LARSSON I.,
EKMAN R.
Publication year - 1983
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1983.tb09797.x
Subject(s) - colostrum , radioimmunoassay , medicine , infant formula , zoology , endocrinology , food science , chemistry , biology , immunology , antibody , pediatrics
. The concentration of tri‐iodothyronine (T 3 ) and thyroxine (T 4 ) in human milk was determined by radioimmunoassay (RIA). The analysis of T 3 was performed on unextracted milk and on ethanol extracts of defatted milk. Analysis of unextracted milk was complicated by artifacts. Reliable and reproducible results were achieved only with the milk extracts. In 10 colostral milk samples the mean T 3 levels ± SD were 0.80 ± 0.52 nmol/l before feeding (early milk) and 0.93 ± 0.62 after feeding (hind milk). The T 3 concentration in colostrum did not change significantly during the feeding to the infant. In 12 mature milk samples collected between infant feedings, the mean T 3 ± SD was 1.19 ± 0.42 nmol/l. T 4 was not detected in any of the samples analysed (detection limit 3 nmol/l).