Premium
LEVELS OF VITAMIN D‐METABOLITES IN A CASE OF ACRO‐OSTEOLYSIS SYNDROME
Author(s) -
SAKANO T.,
HYODO S.,
NISHI Y.,
KOBAYASHI M.,
TANAKA T.,
YAMAOKA K.,
SEINO Y.,
USUI T.
Publication year - 1983
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1983.tb09782.x
Subject(s) - medicine , bone remodeling , osteolysis , vitamin d and neurology , endocrinology , calcifediol , osteoporosis , vitamin d deficiency , surgery
. On the initial examinations of a 17‐year‐old boy with acro‐osteolysis syndrome, the levels of serum 25‐hydroxycholecalciferol (25OHD) were low, whereas serum levels of 1,25‐dihydroxycholecalciferol (1,25(OH) 2 D) were normal. Administration of 1α‐hydroxycholecalciferol (1OHD) failed to improve the osteoporosis, although the serum 25OHD level rose to normal. It is unlikely that impaired bone remodeling due to abnormal vitamin D‐metabolism was a primary defect in our patient.