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ENDOTOXIN CLEARANCE BY EXCHANGE BLOOD TRANSFUSION IN SEPTIC SHOCK NEONATES
Author(s) -
TOGARI H.,
MIKAWA M.,
IWANAGA T.,
MATSUMOTO N.,
KAWASE A.,
HAGISAWA M.,
OGINO T.,
GOTO R.,
WATANABE I.,
KITO H.,
OGAWA Y.,
WADA Y.
Publication year - 1983
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1983.tb09669.x
Subject(s) - medicine , exchange transfusion , septic shock , shock (circulatory) , blood transfusion , whole blood , anesthesia , sepsis , pediatrics , immunology
. The role of exchange transfusion with fresh whole blood in septic shock infants was evaluated. Endotoxin was positive in 8 of 10 infants and completely removed from 6 by exchange transfusion. All 6 infants with negative endotoxins after exchange transfusions survived, but 2 with positive reactions died despite the exchange transfusion. Staphylococcus aureus was cultured in the blood from 2 infants with negative reactions and one of them survived. These findings suggested that the clearance of endotoxin has an important role in exchange transfusion among septic shock neonates.