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PROGNOSIS FOR SURVIVAL WITH CYSTIC FIBROSIS: THE EFFECTS OF EARLY DIAGNOSIS AND CYSTIC FIBROSIS CENTER CARE
Author(s) -
WARWICK WARREN J.
Publication year - 1982
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1982.tb09639.x
Subject(s) - medicine , cystic fibrosis , newborn screening , pediatrics , single center , sweat test
Warwick, W.J. (Department of Pediatrics, University of Minnesota Hospitals, Minneapolis, Minnesota, 55455, U.S.A.) Prognosis for survival with cystic fibrosis: the effects of early diagnosis and cystic fibrosis center care. Acta Paediatr Scand 1982; suppl 301: 27‐31. — Improved diagnosis, i.e. more cystic fibrosis (CF) patients diagnosed at an early age, is possible but will require a great increase in the sensitivity of physicians, providing care for infants and young children, to the possibility that early symptoms could be CF at a time a baby is “too well to have CF” coupled with a simple fast screening type of sweat test. Prognosis for survival for CF patients treated at CF Centers is improved with early diagnosis but the data concerning newborn screening are still too few. The general care of CF patients around the world in the absence of a CF Center shows expected survival of 50 percent to 4 or 5 years of age; addition of a CF Center and a CF Care Team increases that 50 percent survival to 20 years. Improvement in early diagnosis or newborn screening is needed to reduce the number of CF patients who die undiagnosed. CF Center and CF team care increases the survival age of CF patients by 4 to 6 times. Early diagnosis before pulmonary complications have begun more than double the effectiveness of CF Center care. In Denmark, the Paediatric Department TG provides the leadership and training and clinical care and research needed to maintain progress and to improve upon the prognosis for CF. Data from Denmark obtained through the central Danish CF Registry confirm in Denmark these observations from around the world of the benefits of early diagnosis and center treatment. Improvement in early diagnosis or discovery of and general adoption of a newborn screening program is what is needed to reduce the number of CF patients who die undiagnosed. CF Center and CF Team care increases the survival age of CF patients by 4 to 6 times. Early diagnosis before pulmonary complications have begun more than double the effectiveness of CF Center care. In Denmark, the Paediatric Department TG provides the leadership and training and clinical care and research needed to maintain progress and to improve upon the prognosis for CF.