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LONG TERM PULMONARY CONSEQUENCES OF OESOPHAGEAL ATRESIA WITH TRACHEO‐OESOPHAGEAL FISTULA
Author(s) -
COURIEL J. M.,
HIBBERT M.,
OLINSKY A.,
PHELAN P. D.
Publication year - 1982
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1982.tb09559.x
Subject(s) - medicine , spirometry , atresia , plethysmograph , air trapping , lung volumes , tracheoesophageal fistula , pulmonary function testing , cardiology , airway obstruction , respiratory system , asthma , anesthesia , lung , airway
. Lung function was studied in 20 children, aged 8‐17 years, who had successfuly repaired oesophageal atresia with tracheo‐oesophageal fistula. Spirometry and plethysmography showed mild restrictive lung disease. Airways obstruction was assessed using maximal expiratory and inspiratory flow‐volume loops in air and after breathing a helium‐oxygen mixture. Analysis of the flow‐volume data demonstrated significant obstruction at the level of the trachea and little evidence of small airways disease. Bronchial hyperreactivity, as assessed by histamine challenge, was present in 22% of subjects. Respiratory and oesophageal symptoms were common, but decreased in frequency with increasing age. The mechanisms involved in the frequent respiratory symptoms these children suffer are discussed in the light of the physiological findings.